What powers spyre.com?
Last seen Sep 2026 · 41 technologies across 17 categories
Accessibility
AccessiBe
since Jan 2024
Analytics
Adobe Analytics
since Nov 2025
Google Analytics
since Feb 2024
CDN
Akamai
since Nov 2025
Cloudflare
since Jul 2025
Cloudinary
since Nov 2025
Google Hosted Libraries
since Jul 2025
jQuery CDN
since Nov 2025
jsDelivr
since Jul 2025
CMS
Customer data platform
Adobe Experience Platform Identity Service
since Nov 2025
Font scripts
Google Font API
since Jul 2025
Typekit
since Jan 2024
Hosting
JavaScript frameworks
JavaScript libraries
Miscellaneous
PaaS
Page builders
Webflow
since Jul 2025
Programming languages
PHP
since Nov 2025
Security
Tag managers
Adobe Experience Platform Launch
since Nov 2025
Google Tag Manager
since Jan 2024
Video players
Vimeo
since Jul 2025
Webmail
Apple iCloud Mail
since May 2025
AI Crawlers
Doesn't mention any of the 33 AI crawlers we track in its robots.txt; all are allowed by default. Checked Sep 2026.
- robots.txt found
- llms.txt not found
- ai.txt not found
AI Crawlers
No AI crawlers blocked
Audience
- 100% desktop
United States
Where the site's Chrome visitors come from, largest estimated audience first.
Open Page Rank
2.85 / 10 · ranked #1,868,209 of all domains
34 referring domains · OpenPageRank
Core Web Vitals
| LCP | 1 s |
| INP | 25 ms |
| CLS | 0 |
| TTFB | 600 ms |
Real user p75, Chrome UX Report, Sep 2026.
Page
- Language: English
- CDN: Akamai
- Weight: 3.2 MB · 37 requests
- Structured data: JSON-LD, OpenGraph
Homepage as crawled by the HTTP Archive, Sep 2026.
Organisation
- Spyre Therapeutics (Spyre Therapeutics (United States) on Wikidata)
- Founded: 2013
- Country: United States
From the homepage's own structured data (Sep 2026) and Wikidata (CC0).
Infrastructure
- Hosted on Cloudflare (198.202.211.1)
- Email: Proofpoint Essentials
- Email security: SPF (hard fail), DMARC quarantine, DNSSEC signed
- SSL: Google Trust Services, ECDSA P256, expires Nov 2026
- Common Crawl link graph: rank 8,294,575, 3 hosts
- Verified with: Airtable, Apple Business, Google, OpenAI, Rippling, Smartsheet
DNS records as swept Sep 2026, certificate as seen Sep 2026. How the web is hosted
Subdomains
| Host | Techs |
|---|---|
| ir.spyre.com | 25 |
| spyre.com | 14 |
| www.spyre.com | 11 |